Overview

Product Description	Rabbit Polyclonal antibody recognizes FABP4
Tested Reactivity	Hu, Ms, Rat
Tested Application	ICC/IF, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	FABP4
Antigen Species	Human
Immunogen	Synthetic peptide derived from Human FABP4.
Conjugation	Un-conjugated
Alternate Names	Adipocyte lipid-binding protein; Fatty acid-binding protein, adipocyte; aP2; HEL-S-104; AFABP; A-FABP; ALBP; Adipocyte-type fatty acid-binding protein; Fatty acid-binding protein 4

Application Instructions

Application Suggestion	Tested Application Dilution ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	Human fetal heart
Observed Size	15 kDa

Properties

Form	Liquid
Purification	Affinity purified.
Buffer	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 11770 Mouse FABP4 GeneID: 2167 Human FABP4 Swiss-port # P04117 Mouse Fatty acid-binding protein, adipocyte Swiss-port # P15090 Human Fatty acid-binding protein, adipocyte
Gene Symbol	FABP4
Gene Full Name	fatty acid binding protein 4, adipocyte
Background	FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
Function	Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. [UniProt]
Cellular Localization	Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity). [UniProt]
Calculated MW	15 kDa

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