Overview

Product Description	Rabbit Polyclonal antibody recognizes FBXO28
Tested Reactivity	Hu, Ms
Predict Reactivity	Bov
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	FBXO28
Antigen Species	Human
Immunogen	KLH-conjugated synthetic peptide corresponding to aa. 339-368 (C-terminus) of Human FBXO28.
Conjugation	Un-conjugated
Alternate Names	F-box only protein 28; Fbx28; CENP-30

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:1000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	ZR-75-1

Properties

Form	Liquid
Purification	Purification with Protein A and immunogen peptide.
Buffer	PBS and 0.09% (W/V) Sodium azide
Preservative	0.09% (W/V) Sodium azide
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 23219 Human FBXO28 GeneID: 67948 Mouse FBXO28 Swiss-port # Q8BIG4 Mouse F-box only protein 28 Swiss-port # Q9NVF7 Human F-box only protein 28
Gene Symbol	FBXO28
Gene Full Name	F-box protein 28
Background	Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Function	Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. [UniProt]
Calculated MW	41 kDa

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