ARG45886
anti-FGD5 antibody
anti-FGD5 antibody for Western blot,Flow cytometry and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FGD5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FGD5 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human FGD5. |
| Conjugation | Un-conjugated |
| Alternate Names | FYVE, RhoGEF And PH Domain Containing 5; FGD5; ZFYVE23; FYVE, RhoGEF and PH domain-containing protein 5; Zinc finger FYVE domain-containing protein 23 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6ZNL6 Human FYVE, RhoGEF and PH domain-containing protein 5 Swiss-port # Q80UZ0 Mouse FYVE, RhoGEF and PH domain-containing protein 5 |
|---|---|
| Gene Symbol | FGD5 |
| Gene Full Name | FYVE, RhoGEF And PH Domain Containing 5 |
| Background | Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Located in plasma membrane. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. [UniProt] |
| Cellular Localization | Cell membrane; Cell projection; Cytoplasm; Cytoskeleton; Endoplasmic reticulum; Endosome; Golgi apparatus; Membrane. [UniProt] |
| Calculated MW | 160 kDa |
