ARG58703
anti-FMO4 antibody
anti-FMO4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FMO4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FMO4 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 75-92 of Human FMO4 (HEDYPNFMNHEKFWDYLQ). |
| Conjugation | Un-conjugated |
| Alternate Names | FMO2; Hepatic flavin-containing monooxygenase 4; FMO 4; Dimethylaniline oxidase 4; Dimethylaniline monooxygenase [N-oxide-forming] 4; EC 1.14.13.8 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Heat mediated. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FMO4 |
| Gene Full Name | flavin containing monooxygenase 4 |
| Background | Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man. This results in a small subpopulation with reduced TMA N-oxidation capacity and causes fish odor syndrome (Trimethylaminuria). Three forms of the enzyme are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jan 2015] |
| Function | This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. [UniProt] |
| Cellular Localization | Microsome membrane. Endoplasmic reticulum membrane. [UniProt] |
| Calculated MW | 63 kDa |
Images (2) Click the Picture to Zoom In
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ARG58703 anti-FMO4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat liver tissue stained with ARG58703 anti-FMO4 antibody.
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ARG58703 anti-FMO4 antibody WB image
Western blot: Rat liver, Mouse liver, SMMC, HEPA, A431 and MCF7 cell lysates stained with ARG58703 anti-FMO4 antibody.
