ARG11170

anti-FPR2 / FPRL1 antibody

anti-FPR2 / FPRL1 antibody for Flow cytometry,ICC/IF,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes FPR2 / FPRL1
Tested Reactivity Hu
Tested Application FACS, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name FPR2 / FPRL1
Antigen Species Human
Immunogen A short peptide (ASWGGTPEERLKC) corresponding to the amino acids on the 2nd extracellular loop of human FPRL1 is conjugated with KLH for immunization.
Conjugation Un-conjugated
Alternate Names FPR2; Formyl Peptide Receptor 2; LXA4R; HM63; Formyl Peptide Receptor-Like 1; N-Formyl Peptide Receptor 2; FMLP-R-II; FPRH2; FMLPX; FPR2A; FPRL1; ALXR; ALX; FMLP-Related Receptor I; Lipoxin A4 Receptor; LXA4 Receptor; FMLP-R-I; FPRH1; RFP; Lipoxin A4 Receptor (Formyl Peptide Receptor Related)

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
ICC/IF1:400 -1:500
WB1:4000 - 1:5000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G affinity purified
Buffer 0.01M PBS (pH 7.2)
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2358 Human FPR2

Swiss-port # P25090 Human N-formyl peptide receptor 2

Gene Symbol FPR2
Gene Full Name Formyl Peptide Receptor 2
Background Enables amyloid-beta binding activity; scavenger receptor binding activity; and signaling receptor activity. Involved in several processes, including cellular response to amyloid-beta; positive regulation of ERK1 and ERK2 cascade; and regulation of defense response. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Function Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation. [UniProt]
Cellular Localization Cell membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 39 kDa
PTM Disulfide bond, Glycoprotein. [UniProt]