ARG41480
anti-FTCD / 58K Golgi protein antibody
anti-FTCD / 58K Golgi protein antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes FTCD / 58K Golgi protein |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | FTCD / 58K Golgi protein |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 412-541 of Human FTCD / 58K Golgi protein (NP_006648.1). |
| Conjugation | Un-conjugated |
| Alternate Names | EC 2.1.2.5; LCHC1; Formiminotetrahydrofolate cyclodeaminase; Formimidoyltransferase-cyclodeaminase; Formiminotransferase-cyclodeaminase; Glutamate formiminotransferase; Glutamate formyltransferase; FTCD; EC 4.3.1.4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | LO2 | ||||
| Observed Size | ~ 59 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | FTCD |
| Gene Full Name | formimidoyltransferase cyclodeaminase |
| Background | The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009] |
| Function | Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi. [UniProt] |
| Cellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Note=More abundantly located around the mother centriole. [UniProt] |
| Calculated MW | 59 kDa |
Images (1) Click the Picture to Zoom In
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ARG41480 anti-FTCD / 58K Golgi protein antibody WB image
Western blot: 25 µg of LO2 cell lysate stained with ARG41480 anti-FTCD / 58K Golgi protein antibody at 1:1000 dilution.
