ARG45809
anti-Filensin antibody [FIL-7B10]
anti-Filensin antibody [FIL-7B10] for IHC-Frozen sections,Western blot and Bovine,Human
Overview
| Product Description | Mouse Monoclonal antibody [FIL-7B10] recognizes Filensin |
|---|---|
| Tested Reactivity | Hu, Bov |
| Tested Application | IHC-Fr, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | FIL-7B10 |
| Isotype | IgG1 |
| Target Name | Filensin |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | BFSP1; Beaded Filament Structural Protein 1; Filensin; LIFL-H; CP115; CP94; Lens Fiber Cell Beaded-Filament Structural Protein CP 115; Beaded Filament Structural Protein 1, Filensin; Lens Intermediate Filament-Like Heavy Cytoskeletal Protein, 115 KD; CTRCT33 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Ascites |
| Buffer | Mouse ascites fluid, 1.2% Sodium acetate, 0.01 mg Sodium azide and 2 mg BSA. |
| Preservative | 0.01 mg Sodium azide |
| Stabilizer | 2 mg BSA |
| Concentration | 0.1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BFSP1 |
| Gene Full Name | Beaded Filament Structural Protein 1 |
| Background | This gene encodes a lens-specific intermediate filament-like protein named filensin. The encoded protein is expressed in lens fiber cells after differentiation has begun. This protein functions as a component of the beaded filament which is a cytoskeletal structure found in lens fiber cells. Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Function | Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. [UniProt] |
| Cellular Localization | Cell membrane; Cytoplasm; Cytoskeleton; Intermediate filament; Membrane. [UniProt] |
| Calculated MW | 68 kDa |
| PTM | Acetylation; Lipoprotein; Myristate; Phosphoprotein. [UniProt] |
