ARG44647
anti-G-CSF Receptor antibody
anti-G-CSF Receptor antibody for Immunoprecipitation and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes G-CSF Receptor |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | G-CSF Receptor |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | CSF3R; Colony Stimulating Factor 3 Receptor; G-CSF-R; GCSFR; Granulocyte Colony-Stimulating Factor Receptor; Colony Stimulating Factor 3 Receptor (Granulocyte); G-CSF Receptor; CD114 Antigen; CD114; SCN7 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q99062 Human Granulocyte colony-stimulating factor receptor |
|---|---|
| Gene Symbol | CSF3R |
| Gene Full Name | Colony Stimulating Factor 3 Receptor |
| Background | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010] |
| Function | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. [UniProt] |
| Cellular Localization | Cell membrane, Membrane, Secreted. [UniProt] |
| Calculated MW | 92 kDa |
| PTM | Disulfide bond, Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG44647 anti-G-CSF Receptor antibody IP image
Immunoprecipitation: HL-60 lysate immunoprecipitated with 2.5 µg of ARG44647 anti-G-CSF Receptor antibody.
