ARG40083
anti-G2E3 antibody
anti-G2E3 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes G2E3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | G2E3 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-180 of Human G2E3 (NP_060239.2). |
| Conjugation | Un-conjugated |
| Alternate Names | PHF7B; KIAA1333; EC 6.3.2.-; G2/M phase-specific E3 ubiquitin-protein ligase |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Rat testis, Mouse liver and OVCAR3 | ||||
| Observed Size | 80 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q5RJY2 Mouse G2/M phase-specific E3 ubiquitin-protein ligase Swiss-port # Q7L622 Human G2/M phase-specific E3 ubiquitin-protein ligase |
|---|---|
| Gene Symbol | G2E3 |
| Gene Full Name | G2/M-phase specific E3 ubiquitin protein ligase |
| Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. [UniProt] |
| Cellular Localization | Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage. [UniProt] |
| Calculated MW | 81 kDa |
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