ARG58738
anti-GALNT3 antibody
anti-GALNT3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GALNT3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GALNT3 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-140 of Human GALNT3 (NP_004473.2). |
| Conjugation | Un-conjugated |
| Alternate Names | HHS; Protein-UDP acetylgalactosaminyltransferase 3; EC 2.4.1.41; pp-GaNTase 3; HFTC; Polypeptide GalNAc transferase 3; GalNAc-T3; Polypeptide N-acetylgalactosaminyltransferase 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | BT-474 | ||||||||
| Observed Size | 73 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P70419 Mouse Polypeptide N-acetylgalactosaminyltransferase 3 Swiss-port # Q14435 Human Polypeptide N-acetylgalactosaminyltransferase 3 |
|---|---|
| Gene Symbol | GALNT3 |
| Gene Full Name | polypeptide N-acetylgalactosaminyltransferase 3 |
| Background | This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis. [UniProt] |
| Cellular Localization | Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein. [UniProt] |
| Calculated MW | 73 kDa |
Images (1) Click the Picture to Zoom In
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ARG58738 anti-GALNT3 antibody WB image
Western blot: 25 µg of BT-474 cell lysate stained with ARG58738 anti-GALNT3 antibody at 1:1000 dilution.
