ARG45888
anti-GGCT antibody
anti-GGCT antibody for Western blot,Flow cytometry and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GGCT |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GGCT |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human GGCT. |
| Conjugation | Un-conjugated |
| Alternate Names | GGCT; Gamma-Glutamylcyclotransferase; CRF21; C7orf24; Cytochrome C-Releasing Factor 21; MGC3077; GCTG; Ggc; Chromosome 7 Open Reading Frame 24; Gamma -Glutamyl Cyclotransferase; EC 4.3.2.9; GGC |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 21 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GGCT |
| Gene Full Name | Gamma-Glutamylcyclotransferase |
| Background | The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
| Function | Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. [UniProt] |
| Cellular Localization | Cytosol, Extracellular exosome. [UniProt] |
| Calculated MW | 21 kDa |
| PTM | Phosphoprotein. [UniProt] |
