ARG10204
anti-GM-CSF antibody [429] (HRP)
anti-GM-CSF antibody [429] (HRP) for ELISA and Human
Immune System antibody
Overview
| Product Description | HRP-conjugated Mouse Monoclonal antibody [429] recognizes GM-CSF |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Does not show any cross reaction with other human cytokines or growth factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL-1β, TGF-β1 and TNF-α. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 429 |
| Isotype | IgG1, kappa |
| Target Name | GM-CSF |
| Antigen Species | Human |
| Immunogen | Purified recombinant human GM-CSF |
| Conjugation | HRP |
| Alternate Names | GM-CSF; Granulocyte-macrophage colony-stimulating factor; CSF; GMCSF; Molgramostin; Colony-stimulating factor; Sargramostim |
Application Instructions
| Application Note | ELISA: In combination with a monoclonal capture antibody clone 59 (Cat. No.: ARG10032), this HRP conjugated antibody can be used as a tracer antibody in sandwich ELISA applications for human GM-CSF detection. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G affinity purified |
| Buffer | 0.01M PBS (pH 7.2) and 50% Glycerol |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Keep the antibody in the dark and keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P04141 Human Granulocyte-macrophage colony-stimulating factor |
|---|---|
| Gene Symbol | CSF2 |
| Gene Full Name | colony stimulating factor 2 (granulocyte-macrophage) |
| Background | GM-CSF is an extracellular homodimer polyprotein, functioning as a hematopoietic growth factor and immune modulator. It can be produced and act upon a variety of cell types, including T-lymphocytes, B-lymphocytes, monocytes/macrophages, endothelial cells, fibroblasts, stromal cells, mesothelial cells, keratinocytes, osteoblasts, uterine epithelial cells, synoviocytes, mast cells and various solid tumors. GM-CSF stimulates stem cells to produce granulocytes and monocytes to cope with infection. Recombinant GM-CSF has been applied to boost white blood cell in cancer patients after chemotherapy and may also be useful as an immune tonic for anemia and AIDS patients. |
| Function | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. [UniProt] |
| Highlight | Related Antibody Duos and Panels: ARG30076 GM-CSF ELISA Antibody Duo Related products: GM-CSF antibodies; GM-CSF ELISA Kits; GM-CSF Duos / Panels; GM-CSF recombinant proteins; Anti-Mouse IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
| Research Area | Immune System antibody |
| Calculated MW | 16 kDa |
