ARG58894
anti-GNGT1 antibody
anti-GNGT1 antibody for ICC/IF,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes GNGT1 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | GNGT1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-45 of Human GNGT1 (NP_068774.1). |
| Conjugation | Un-conjugated |
| Alternate Names | GNG1; Guanine nucleotide-binding protein G(T) subunit gamma-T1; Transducin gamma chain |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Rat eye | ||||||
| Observed Size | 10 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q61012 Mouse Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
|---|---|
| Gene Symbol | GNGT1 |
| Gene Full Name | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
| Background | Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626]; Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008] |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. [UniProt] |
| Cellular Localization | Cell membrane, Cytoplasmic side, Lipid-anchor. [UniProt] |
| Calculated MW | 8 kDa |
Images (1) Click the Picture to Zoom In
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ARG58894 anti-GNGT1 antibody WB image
Western blot: 25 µg of Rat eye lysate stained with ARG58894 anti-GNGT1 antibody at 1:1000 dilution.
