ARG66975

anti-GON4L antibody

anti-GON4L antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes GON4L
Tested Reactivity Hu, Ms
Predict Reactivity Rat
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name GON4L
Antigen Species Human
Immunogen Synthetic peptide around the middle region of Human GON4L.
Conjugation Un-conjugated
Protein Full Name GON-4-like protein
Alternate Names GON4; YARP; GON-4; GON-4 homolog; KIAA1606

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:200–1:500
IHC-P1:50 - 1:500
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~250-260 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol.
Preservative 0.025% ProClin 300
Stabilizer 20% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 54856 Human GON4L

Swiss-port # Q3T8J9 Human GON-4-like protein

Gene Symbol GON4L
Gene Full Name gon-4 like
Background Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription, DNA templated. Predicted to act upstream of or within B cell differentiation. Located in nuclear body. [provided by Alliance of Genome Resources, Apr2022]
Function Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A and HDAC1. Required for B cell lymphopoiesis. [UniProt]
Cellular Localization Nucleus
Calculated MW 248.6 kDa
PTM Phosphoprotein

Images (3) Click the Picture to Zoom In

  • ARG66975 anti-GON4L antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded mouse testis stained with ARG66975 anti-GON4L antibody IHC-P image at 1:400 dilution.

  • ARG66975 anti-GON4L antibody ICC/IF image

    Immunofluorescence: 4% paraformaldehyde-fixed A549 cells were permeabilized with 0.1% NP-40 for 5-10 minutes and blocked with 5% BSA for 30 minutes at room temperature. Cells were stained with ARG66975 anti-GON4L antibody at 1:300 dilution.

  • ARG66975 anti-GON4L antibody WB image

    Western blot: A549 cells stained with ARG66975 anti-GON4L antibody at 1:1000 dilution.