ARG57070
anti-GPD1L antibody [14E2]
anti-GPD1L antibody [14E2] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [14E2] recognizes GPD1L |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 14E2 |
| Isotype | IgG1, kappa |
| Target Name | GPD1L |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-351 of Human GPD1L. |
| Conjugation | Un-conjugated |
| Alternate Names | Glycerol-3-phosphate dehydrogenase 1-like protein; GPD1-L; EC 1.1.1.8 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8N335 Human Glycerol-3-phosphate dehydrogenase 1-like protein |
|---|---|
| Gene Symbol | GPD1L |
| Gene Full Name | glycerol-3-phosphate dehydrogenase 1-like |
| Background | The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010] |
| Function | Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L. [UniProt] |
| Calculated MW | 38 kDa |
Images (2) Click the Picture to Zoom In
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ARG57070 anti-GPD1L antibody [14E2] WB image
Western blot: 40 µg of 1) MCF7 cell lysate, 2) 293T cell lysate, 3) Jurkat cell lysate, 4) SW480 cell lysate, 5) PC3 cell lysate stained with ARG57070 anti-GPD1L antibody [14E2] at 1:500.
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ARG57070 anti-GPD1L antibody [14E2] WB image
Western blot: 40 µg of 1) 293T cell lysate, 2) GPD1L Transfected 293T cell lysate stained with ARG57070 anti-GPD1L antibody [14E2] at 1:1000.
