ARG67257
anti-GSDMD (cleaved) antibody
anti-GSDMD (cleaved) antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Monoclonal antibody recognizes GSDMD (cleaved) |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Rat |
| Tested Application | ICC/IF, WB |
| Specificity | ARG67257 detects endogenous levels of Cleaved N-terminal GSDMD. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG, Kappa |
| Target Name | GSDMD (cleaved) |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | GSDMD; Gasdermin D; GSDMDC1; DF5L; Gasdermin Domain-Containing Protein 1; Gasdermin Domain Containing 1; Gasdermin-D; FLJ12150; DFNA5L ; FKSG10 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 53, 36 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A affinity purified |
| Buffer | PBS, 0.05% Proclin 300, 50% Glycerol and 0.05% BSA. |
| Preservative | 0.05% Proclin 300 |
| Stabilizer | 50% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GSDMD |
| Gene Full Name | Gasdermin D |
| Background | Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
| Function | Does not bind to unphosphorylated phosphatidylinositol, phosphatidylethanolamine nor phosphatidylcholine. [Uniprot] |
| Cellular Localization | Cell membrane, Cytoplasm, Inflammasome, Membrane, Mitochondrion, Nucleus, Secreted. [Uniprot] |
| Calculated MW | 53 kDa |
| PTM | Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein, Ubl conjugation. [Uniprot] |
