ARG45360
anti-HGFA Inhibitor 2 antibody [7F52]
anti-HGFA Inhibitor 2 antibody [7F52] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody [7F52] recognizes HGFA Inhibitor 2 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 7F52 |
| Isotype | IgG2 |
| Target Name | HGFA Inhibitor 2 |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse HGFA Inhibitor 2. |
| Conjugation | Un-conjugated |
| Alternate Names | SPINT2; Serine Peptidase Inhibitor, Kunitz Type 2; HAI-2; HAI2; Kop; Kunitz Domain Containing Protein Overexpressed In Pancreatic Cancer; Hepatocyte Growth Factor Activator Inhibitor Type 2; Hepatocyte Growth Factor Activator Inhibitor-2; Serine Protease Inhibitor, Kunitz Type, 2; Kunitz-Type Protease Inhibitor 2; HGF Activator Inhibitor 2; Placental Bikunin; Testicular Tissue Protein Li 183; DIAR3; KOP; PB |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G/A chromatography |
| Buffer | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SPINT2 |
| Gene Full Name | Serine Peptidase Inhibitor, Kunitz Type 2 |
| Background | This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
| Function | Inhibitor of HGFAC |
| Cellular Localization | Cell membrane; Cytoplasm; Membrane. [UniProt] |
| Calculated MW | 28 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
