ARG64135
anti-HNF1 beta / vHNF1 antibody
anti-HNF1 beta / vHNF1 antibody for ICC/IF,Western blot and Human
Gene Regulation antibody; Metabolism antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes HNF1 beta / vHNF1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Pig, Zfsh |
| Tested Application | ICC/IF, WB |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_000449.1; NP_001159395.1). This product may cross-react with HNF1A. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | HNF1 beta / vHNF1 |
| Antigen Species | Human |
| Immunogen | C-QAYDRQKNPSKEER |
| Conjugation | Un-conjugated |
| Alternate Names | TCF-2; vHNF1; TCF2; FJHN; HNF1beta; Variant hepatic nuclear factor 1; HNF-1B; Hepatocyte nuclear factor 1-beta; HPC11; Homeoprotein LFB3; VHNF1; MODY5; Transcription factor 2; HNF2; LFB3; HNF-1-beta; LF-B3 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| Research Area | Gene Regulation antibody; Metabolism antibody |
| Calculated MW | 61 kDa |
Images (1) Click the Picture to Zoom In
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ARG64135 anti-HNF1 beta / vHNF1 antibody WB image
Western Blot: Human Liver lysate (35 µg protein in RIPA buffer) stained with ARG64135 anti-HNF1 beta / vHNF1 antibody at 0.1 µg/ml dilution.
