ARG66648

anti-HOXD8 antibody

anti-HOXD8 antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes HOXD8
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name HOXD8
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide within the C-terminal region of Human HOXD8.
Conjugation Un-conjugated
Alternate Names Homeobox protein Hox-4E; HOX4; HOX4E; HOX5.4; Homeobox protein Hox-D8; Homeobox protein Hox-5.4

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 32 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol.
Preservative 0.01% Sodium azide
Stabilizer 30% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 15437 Mouse HOXD8

GeneID: 3234 Human HOXD8

Swiss-port # P13378 Human Homeobox protein Hox-D8

Swiss-port # P23463 Mouse Homeobox protein Hox-D8

Gene Symbol HOXD8
Gene Full Name homeobox D8
Background This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 32 kDa

Images (2) Click the Picture to Zoom In

  • ARG66648 anti-HOXD8 antibody WB image

    Western blot: A375, A431, HepG2 and HeLa whole cell lysates stained with ARG66648 anti-HOXD8 antibody.

  • ARG66648 anti-HOXD8 antibody WB image

    Western blot: Mouse kidney and Rat kidney lysates stained with ARG66648 anti-HOXD8 antibody.