ARG45572
anti-Haspin antibody
anti-Haspin antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Haspin |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Haspin |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Haspin. |
| Conjugation | Un-conjugated |
| Alternate Names | HASPIN; Histone H3 Associated Protein Kinase; GSG2; Haploid Germ Cell-Specific Nuclear Protein Kinase; Serine/Threonine-Protein Kinase Haspin; Germ Cell-Specific Gene 2 Protein; H-Haspin; Germ Cell Associated 2 (Haspin); Germ Cell Associated 2, Haspin; EC 2.7.11.1 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 88 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8TF76 Human Serine/threonine-protein kinase haspin Swiss-port # Q9Z0R0 Mouse Serine/threonine-protein kinase haspin |
|---|---|
| Gene Symbol | HASPIN |
| Gene Full Name | Histone H3 Associated Protein Kinase |
| Background | Enables ATP binding activity and histone H3T3 kinase activity. Involved in several processes, including mitotic sister chromatid cohesion; mitotic spindle assembly checkpoint signaling; and protein localization to chromosome, centromeric region. Located in centrosome; nucleoplasm; and spindle. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle. ( HASP_HUMAN,Q8TF76 ). [UniProt] |
| Cellular Localization | Chromosome; Cytoplasm; Cytoskeleton; Nucleus. [UniProt] |
| Calculated MW | 88 kDa |
| PTM | Phosphoprotein. [UniProt] |
