ARG44373
anti-ING5 antibody
anti-ING5 antibody for ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ING5 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ING5 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ING5 |
| Conjugation | Un-conjugated |
| Alternate Names | ING5; Inhibitor Of Growth Family Member 5; P28ING5; Inhibitor Of Growth Protein 5; FLJ23842 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% sodium azide and 50% Glycerol. |
| Preservative | 0.02% sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ING5 |
| Gene Full Name | Inhibitor Of Growth Family Member 5 |
| Background | This gene encodes a tumor suppressor protein that inhibits cell growth and induces apoptosis. This protein contains a PHD-type zinc finger. It interacts with tumor suppressor p53 and p300, a component of the histone acetyl transferase complex, suggesting a role in transcriptional regulation. Alternative splicing and the use of multiple promoters and 3' terminal exons results in multiple transcript variants. |
| Function | Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4. |
| Cellular Localization | Chromosome, Nucleus |
| Calculated MW | 28 kDa |
| PTM | Acetylation, Methylation, Phosphoprotein |
Images (2) Click the Picture to Zoom In
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ARG44373 anti-ING5 antibody ICC/IF image
Immunofluorescence: MCF-7 stained with ARG44373 anti-ING5 antibody at 1:50 dilution.
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ARG44373 anti-ING5 antibody WB image
Western blot: 293T and ING5 KO 293T stained with ARG44373 anti-ING5 antibody at 1:1000 dilution.
