ARG44480
anti-INTS12 antibody
anti-INTS12 antibody for Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes INTS12 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | INTS12 |
| Antigen Species | Human |
| Immunogen | Human INTS12 recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | INTS12; Integrator Complex Subunit 12; PHD Finger Protein 22; SBBI22; INT12; PHF22; Hypothetical Nuclear Factor SBBI22; Int12 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | INTS12 |
| Gene Full Name | Integrator Complex Subunit 12 |
| Background | INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2. |
| Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
| Cellular Localization | Nucleus |
| Calculated MW | 49 kDa |
| PTM | Isopeptide bond, Phosphoprotein, Ubl conjugation |
Images (4) Click the Picture to Zoom In
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ARG44480 anti-INTS12 antibody WB image
Western blot: HepG2, K562, Jurkat and HEL stained with ARG44480 anti-INTS12 antibody at 0.5 μg/mL dilution.
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ARG44480 anti-INTS12 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44480 anti-INTS12 antibody at 1 μg/10^6 cells dilution.
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ARG44480 anti-INTS12 antibody WB image
Western blot: PC-12 and NRK stained with ARG44480 anti-INTS12 antibody at 0.5 μg/mL dilution.
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ARG44480 anti-INTS12 antibody WB image
Western blot: RAW264.7 and SP2/0 stained with ARG44480 anti-INTS12 antibody at 0.5 μg/mL dilution.
