ARG40407
anti-IRAK2 antibody
anti-IRAK2 antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IRAK2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Specificity | At least four isoforms of IRAK2 are known to exist; this antibody will detect all four isoforms. The antibody has no cross-reactivity with IRAK1. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IRAK2 |
| Antigen Species | Mouse |
| Immunogen | A peptide (17 amino acids) within the last 50 amino acids of Mouse IRAK2. |
| Conjugation | Un-conjugated |
| Alternate Names | IRAK-2; Interleukin-1 receptor-associated kinase-like 2 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Raw264.7 |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O43187 Human Interleukin-1 receptor-associated kinase-like 2 Swiss-port # Q8CFA1 Mouse Interleukin-1 receptor-associated kinase-like 2 |
|---|---|
| Gene Symbol | IRAK2 |
| Gene Full Name | interleukin-1 receptor-associated kinase 2 |
| Background | IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq, Jul 2008] |
| Function | Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. [UniProt] |
| Calculated MW | 69 kDa |
Images (4) Click the Picture to Zoom In
-
ARG40407 anti-IRAK2 antibody ICC/IF image
Immunofluorescence: A20 cells stained with ARG40407 anti-IRAK2 antibody at 10 µg/ml dilution.
-
ARG40407 anti-IRAK2 antibody WB image
Western blot: Raw264.7 whole cell lysate stained with ARG40407 anti-IRAK2 antibody at 0.5, 1 and 2 µg/ml dilution.
-
ARG40407 anti-IRAK2 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG40407 anti-IRAK2 antibody (red) at 20 µg/ml dilution. DAPI (blue) for nuclear staining.
-
ARG40407 anti-IRAK2 antibody ICC image
Immunocytochemistry: A20 cells stained with ARG40407 anti-IRAK2 antibody at 1 µg/ml dilution.
