ARG23747
anti-J Chain antibody [Mc19-9]
anti-J Chain antibody [Mc19-9] for ELISA,IHC-Frozen sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [Mc19-9] recognizes J Chain. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IHC-Fr, IP, WB |
| Specificity | The antibody reacts with human J chain as tested by ELISA using purified human Ig fragments as the solid phase target antigen. The antibody does not detect J chain in intact IgM in ELISA assays due to steric hindrance. In Western blotting techniques this antibody detects J chain in IgM only under reducing conditions. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Mc19-9 |
| Isotype | IgG1 |
| Target Name | J Chain |
| Antigen Species | Human |
| Immunogen | Human J Chain. |
| Conjugation | Un-conjugated |
| Alternate Names | Joining chain of multimeric IgA and IgM; Immunoglobulin J chain; IGCJ; JCH; IGJ |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | TRIS buffered saline and 0.09% Sodium azide. |
| Preservative | 0.09% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | JCHAIN |
| Gene Full Name | joining chain of multimeric IgA and IgM |
| Function | Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. [UniProt] |
| Calculated MW | 18 kDa |
