ARG44435
anti-JOSD2 / Josephin2 antibody
anti-JOSD2 / Josephin2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes JOSD2 / Josephin2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | JOSD2 / Josephin2 |
| Antigen Species | Human |
| Immunogen | Human JOSD2 / Josephin2 recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | JOSD2; Josephin Domain Containing 2; SBBI54; Josephin Domain-Containing Protein 2; Josephin-2 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | JOSD2 |
| Gene Full Name | Josephin Domain Containing 2 |
| Background | This gene encodes a protein containing a Josephin domain. Josephin domain-containing proteins are deubiquitinating enzymes which catalyze the hydrolysis of the bond between the C-terminal glycine of the ubiquitin peptide and protein substrates. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Function | Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 21 kDa |
Images (5) Click the Picture to Zoom In
-
ARG44435 anti-JOSD2 / Josephin2 antibody IHC-P image
Immunohistochemistry: Human esophageal squamous carcinoma stained with ARG44435 anti-JOSD2 / Josephin2 antibody at 2 μg/mL dilution.
-
ARG44435 anti-JOSD2 / Josephin2 antibody WB image
Western blot: A549, PC-3 and MCF-7 stained with ARG44435 anti-JOSD2 / Josephin2 antibody at 0.5 μg/mL dilution.
-
ARG44435 anti-JOSD2 / Josephin2 antibody FACS image
Flow Cytometry: HEL stained with ARG44435 anti-JOSD2 / Josephin2 antibody at 1 μg/10^6 cells dilution.
-
ARG44435 anti-JOSD2 / Josephin2 antibody WB image
Western blot: Rat liver stained with ARG44435 anti-JOSD2 / Josephin2 antibody at 0.5 μg/mL dilution.
-
ARG44435 anti-JOSD2 / Josephin2 antibody WB image
Western blot: Mouse liver stained with ARG44435 anti-JOSD2 / Josephin2 antibody at 0.5 μg/mL dilution.
