ARG23297

anti-Jagged 2 antibody [HMJ2-1]

anti-Jagged 2 antibody [HMJ2-1] for Flow cytometry,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Hamster Monoclonal antibody [HMJ2-1] recognizes Jagged 2
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, IHC-Fr, IHC-P
Host Hamster
Clonality Monoclonal
Clone HMJ2-1
Isotype IgG
Target Name Jagged 2
Antigen Species Mouse
Immunogen Jagged2-expressing CHO cells.
Conjugation Un-conjugated
Alternate Names Protein jagged-2; hJ2; Jagged2; SER2; HJ2

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
IHC-FrAssay-dependent
IHC-PAssay-dependent
Application Note FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% Sodium azide.
Preservative 0.09% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16450 Mouse JAG2

GeneID: 3714 Human JAG2

Swiss-port # Q9QYE5 Mouse Protein jagged-2

Swiss-port # Q9Y219 Human Protein jagged-2

Gene Symbol JAG2
Gene Full Name jagged 2
Background The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity). [UniProt]
Calculated MW 133 kDa

Images (2) Click the Picture to Zoom In

  • ARG23297 anti-Jagged 2 antibody [HMJ2-1] FACS image

    Flow Cytometry: Mouse Jagged 2 transfected cells stained with ARG23297 anti-Jagged 2 antibody [HMJ2-1].

  • ARG23297 anti-Jagged 2 antibody [HMJ2-1] IHC-P image

    Immunohistochemistry: Paraffin-embedded Human testis stained with ARG23297 anti-Jagged 2 antibody [HMJ2-1] followed by Goat anti Hamster IgG (HRP).