ARG40013
anti-LARP7 antibody
anti-LARP7 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LARP7 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LARP7 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 160-380 of Human LARP7 (NP_057732.2). |
| Conjugation | Un-conjugated |
| Alternate Names | PIP7S; ALAZS; P-TEFb-interaction protein for 7SK stability; La-related protein 7; HDCMA18P; La ribonucleoprotein domain family member 7 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse testis and U-87MG | ||||
| Observed Size | 71 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LARP7 |
| Gene Full Name | La ribonucleoprotein domain family, member 7 |
| Background | This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012] |
| Function | Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. [UniProt] |
| Cellular Localization | Nucleus, nucleoplasm. [UniProt] |
| Calculated MW | 67 kDa |
Images (1) Click the Picture to Zoom In
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ARG40013 anti-LARP7 antibody WB image
Western blot: 25 µg of Mouse testis and U-87MG cell lysates stained with ARG40013 anti-LARP7 antibody at 1:3000 dilution.
