ARG41203
anti-LPIN2 / Lipin 2 antibody
anti-LPIN2 / Lipin 2 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LPIN2 / Lipin 2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LPIN2 / Lipin 2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 180-400 of Human LPIN2 / Lipin 2 (NP_055461.1). |
| Conjugation | Un-conjugated |
| Alternate Names | EC 3.1.3.4; Phosphatidate phosphatase LPIN2; Lipin-2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | A549 | ||||
| Observed Size | 110 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | LPIN2 |
| Gene Full Name | lipin 2 |
| Background | Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008] |
| Function | Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity). [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane. Note=Translocates to endoplasmic reticulum membrane with increasing levels of oleate. [UniProt] |
| Calculated MW | 99 kDa |
Images (1) Click the Picture to Zoom In
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ARG41203 anti-LPIN2 / Lipin 2 antibody WB image
Western blot: 25 µg of A549 cell lysate stained with ARG41203 anti-LPIN2 / Lipin 2 antibody at 1:1000 dilution.
