ARG45202
anti-LSM5 antibody
anti-LSM5 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes LSM5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LSM5 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human LSM5. |
| Conjugation | Un-conjugated |
| Alternate Names | LSM5; LSM5 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated; YER146W; U6 SnRNA-Associated Sm-Like Protein LSm5; LSM5 Homolog, U6 Small Nuclear RNA Associated (S. Cerevisiae); LSM5 U6; Small Nuclear RNA And MRNA Degradation Associated; LSM5 Homolog, U6 Small Nuclear RNA Associated |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 12 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P62322 Mouse U6 snRNA-associated Sm-like protein LSm5 Swiss-port # Q9Y4Y9 Human U6 snRNA-associated Sm-like protein LSm5 |
|---|---|
| Gene Symbol | LSM5 |
| Gene Full Name | LSM5 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated |
| Background | U6 snRNA-associated Sm-like protein LSm5 is a protein that in humans is encoded by the LSM5 gene. Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. |
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 10 kDa |
| PTM | Acetylation. [UniProt] |
