Overview

Product Description	Rabbit Polyclonal antibody recognizes LSS
Tested Reactivity	Hu, Ms
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	LSS
Antigen Species	Human
Immunogen	Recombinant protein of Human LSS.
Conjugation	Un-conjugated
Alternate Names	hOSC; 2,3-epoxysqualene--lanosterol cyclase; Oxidosqualene--lanosterol cyclase; EC 5.4.99.7; OSC; Lanosterol synthase

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	Mouse lung

Properties

Form	Liquid
Purification	Affinity purification with immunogen.
Buffer	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 16987 Mouse LSS GeneID: 4047 Human LSS Swiss-port # P48449 Human Lanosterol synthase Swiss-port # Q8BLN5 Mouse Lanosterol synthase
Gene Symbol	LSS
Gene Full Name	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Background	The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]
Function	Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. [UniProt]
Calculated MW	83 kDa

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