ARG45903
anti-MAML3 antibody
anti-MAML3 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF,Flow cytometry and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MAML3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MAML3 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human MAML3. |
| Conjugation | Un-conjugated |
| Alternate Names | Mastermind Like Transcriptional Coactivator 3; MAML3; KIAA1816; Mastermind-like protein 3; Mam-3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 140 - 150 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MAML3 |
| Gene Full Name | Mastermind Like Transcriptional Coactivator 3 |
| Background | Enables transcription coactivator activity. Involved in Notch signaling pathway and positive regulation of transcription by RNA polymerase II. Located in nuclear speck. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 122 kDa |
| PTM | Acetylation. [UniProt] |
