ARG40366
anti-MANBA antibody
anti-MANBA antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MANBA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MANBA |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 712-745 of Human MANBA. |
| Conjugation | Un-conjugated |
| Alternate Names | Lysosomal beta A mannosidase; EC 3.2.1.25; Mannanase; MANB1; Mannase; Beta-mannosidase |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HCT116 | ||||
| Observed Size | ~ 100 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MANBA |
| Gene Full Name | mannosidase, beta A, lysosomal |
| Background | This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008] |
| Function | Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. [UniProt] |
| Cellular Localization | Lysosome. [UniProt] |
| Calculated MW | 101 kDa |
Images (1) Click the Picture to Zoom In
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ARG40366 anti-MANBA antibody WB image
Western blot: 20 µg of HCT116 whole cell lysate stained with ARG40366 anti-MANBA antibody at 1:2000 dilution.
