ARG45752
anti-MAP4K3 antibody
anti-MAP4K3 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MAP4K3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MAP4K3 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human MAP4K3. |
| Conjugation | Un-conjugated |
| Alternate Names | MAP4K3; Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3; GLK; MAPKKKK3; RAB8IPL1; Germinal Center Kinase-Related Protein Kinase; MAPK/ERK Kinase Kinase Kinase 3; MEK Kinase Kinase 3; EC 2.7.11.1 47; MEKKK 3; Germinal Center Kinase-Like Kinase; EC 2.7.11 47; MEKKK3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 100 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MAP4K3 |
| Gene Full Name | Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 |
| Background | This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| Function | Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 101 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
