ARG44188
anti-METAP1D antibody
anti-METAP1D antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes METAP1D |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | METAP1D |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human METAP1D |
| Conjugation | Un-conjugated |
| Protein Full Name | Methionine aminopeptidase 1D, mitochondrial |
| Alternate Names | METAP1D; Methionyl Aminopeptidase Type 1D, Mitochondrial; MAP1D; MetAP 1D; Metap1l; Methionine Aminopeptidase 1D, Mitochondrial; Peptidase M 1D; MAP 1D; CDS Of MetAP-3 Within PCR Fragment; Methionine Aminopeptidase 1D; EC 3.4.11.18 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6UB28 Human Methionine aminopeptidase 1D, mitochondrial Swiss-port # Q9CPW9 Mouse Methionine aminopeptidase 1D, mitochondrial |
|---|---|
| Gene Symbol | METAP1D |
| Gene Full Name | Methionyl Aminopeptidase Type 1D, Mitochondrial |
| Background | The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]). |
| Function | Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. |
| Cellular Localization | Mitochondrion |
| Calculated MW | 37 kDa |
Images (4) Click the Picture to Zoom In
-
ARG44188 anti-METAP1D antibody IHC-P image
Immunohistochemistry: Human colorectal adenocarcinoma stained with ARG44188 anti-METAP1D antibody at 2 μg/mL dilution.
-
ARG44188 anti-METAP1D antibody WB image
Western blot: 293T and HepG2 stained with ARG44188 anti-METAP1D antibody at 0.5 μg/mL dilution.
-
ARG44188 anti-METAP1D antibody WB image
Western blot: Rat liver and RH35 stained with ARG44188 anti-METAP1D antibody at 0.5 μg/mL dilution.
-
ARG44188 anti-METAP1D antibody WB image
Western blot: Neuro-2a stained with ARG44188 anti-METAP1D antibody at 0.5 μg/mL dilution.
