ARG21073

anti-MHC Class I H2 Db antibody [28-14-8] (Biotin)

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100 μg

379.00

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Overview

Product Description	Biotin-conjugated Mouse Monoclonal antibody [28-14-8] recognizes MHC Class I H2 Db
Tested Reactivity	Ms
Tested Application	BL, FACS, IHC-Fr
Specificity	The clone 28-14-8 binds to the α3 domain of H-2Db in the presence or absence of β2 microglobulin. It cross reacts with the α3 domain of H-2Ld, but not Kd or Dd, and with H-2Dq and/or Lq. 28-14-8 can block H-2Ld-specific and H-2Ld-restricted antigen-specific lysis of target cells by cytotoxic T lymphocytes but it does not block recognition of H-2Ld-positive target cells by Ly-6G2-positive NK cells.
Host	Mouse
Clonality	Monoclonal
Clone	28-14-8
Isotype	IgG2a, kappa
Target Name	MHC Class I H2 Db
Antigen Species	Mouse
Immunogen	C3H.SW mouse splenocytes
Conjugation	Biotin
Alternate Names	H-2 class I histocompatibility antigen, D-B alpha chain; H2-D; B; H-2D

Application Instructions

Application Suggestion

Application Note

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Buffer	PBS and 0.1% Sodium azide.
Preservative	0.1% Sodium azide
Concentration	0.5 mg/ml
Storage Instruction	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 14964 Mouse H2-D1 Swiss-port # P01899 Mouse H-2 class I histocompatibility antigen, D-B alpha chain
Gene Symbol	H2-D1
Gene Full Name	histocompatibility 2, D region locus 1
Function	Involved in the presentation of foreign antigens to the immune system. [UniProt]
Calculated MW	41 kDa