ARG45371
anti-MMRN2 antibody [2063E2A11]
anti-MMRN2 antibody [2063E2A11] for ICC/IF,IHC-Frozen sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody [2063E2A11] recognizes MMRN2 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ICC/IF, IHC-Fr |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 2063E2A11 |
| Target Name | MMRN2 |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse MMRN2. |
| Conjugation | Un-conjugated |
| Alternate Names | MMRN2; Multimerin 2; Elastin Microfibril Interfacer 3; EndoGlyx-1; EMILIN3; Elastin Microfibril Interface Located Protein 3; EndoGlyx-1 P125/P140 Subunit; Multimerin-2; FLJ13465; EMILIN-3; EMILIN-Like Protein EndoGlyx-1; EndoGlyx-1 P125/P140 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein G chromatography |
| Buffer | PBS |
| Concentration | 0.1 - 1.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MMRN2 |
| Gene Full Name | Multimerin 2 |
| Background | This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012] |
| Function | Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor. |
| Cellular Localization | Extracellular matrix; Secreted. [UniProt] |
| Calculated MW | 105 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
