ARG59834
anti-MRGPRX1 / MRGX1 antibody
anti-MRGPRX1 / MRGX1 antibody for Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MRGPRX1 / MRGX1 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MRGPRX1 / MRGX1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 263-322 of Human MRGPRX1 (NP_671732.3). |
| Conjugation | Un-conjugated |
| Alternate Names | SNSR4; MRGX1; MGRG2; Sensory neuron-specific G-protein coupled receptor 3/4; GPCR; Mas-related G-protein coupled receptor member X1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Rat liver and Mouse liver | ||||
| Observed Size | 36 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8CIP3 Mouse Mas-related G-protein coupled receptor member X1 |
|---|---|
| Gene Symbol | MRGPRX1 |
| Gene Full Name | MAS-related GPR, member X1 |
| Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner. [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 36 kDa |
Images (1) Click the Picture to Zoom In
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ARG59834 anti-MRGPRX1 / MRGX1 antibody WB image
Western blot: 25 µg of Rat liver and Mouse liver lysates stained with ARG59834 anti-MRGPRX1 / MRGX1 antibody at 1:3000 dilution.
