ARG40450
anti-MSH4 antibody
anti-MSH4 antibody for Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MSH4 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MSH4 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 697-936 of Human MSH4 (NP_002431.2). |
| Conjugation | Un-conjugated |
| Alternate Names | MutS protein homolog 4; hMSH4 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse skeletal muscle | ||||
| Observed Size | 105 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MSH4 |
| Gene Full Name | mutS homolog 4 |
| Background | This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. [provided by RefSeq, Aug 2011] |
| Function | Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis. [UniProt] |
| Calculated MW | 105 kDa |
Images (1) Click the Picture to Zoom In
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ARG40450 anti-MSH4 antibody WB image
Western blot: 25 µg of Mouse skeletal muscle lysate stained with ARG40450 anti-MSH4 antibody at 1:1000 dilution.
