ARG66547
anti-MYBL2 / B MYB phospho (Ser577) antibody
anti-MYBL2 / B MYB phospho (Ser577) antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MYBL2 / B MYB phospho (Ser577) |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MYBL2 / B MYB |
| Antigen Species | Human |
| Immunogen | Phosphospecific peptide around Ser577 of Human MYBL2. |
| Conjugation | Un-conjugated |
| Alternate Names | B-MYB; Myb-related protein B; B-Myb; BMYB; Myb-like protein 2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 30% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MYBL2 |
| Gene Full Name | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| Background | The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
| Function | Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 79 kDa |
| PTM | Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG66547 anti-MYBL2 / B MYB phospho (Ser577) antibody WB image
Western blot: MCF7, HeLa, Mouse liver and Rat liver lysates stained with ARG66547 anti-MYBL2 / B MYB phospho (Ser577) antibody.
