ARG56525
anti-Melanocortin 4 Receptor antibody
anti-Melanocortin 4 Receptor antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Melanocortin 4 Receptor |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Melanocortin 4 Receptor |
| Antigen Species | Mouse |
| Immunogen | Synthetic peptide around the N-terminus of Mouse Melanocortin-4 Receptor. |
| Conjugation | Un-conjugated |
| Alternate Names | MC4-R; MC4R; Melanocortin receptor 4 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MC4R |
| Gene Full Name | melanocortin 4 receptor |
| Background | The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010] |
| Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). [UniProt] |
| Cellular Localization | Cell membrane; Multi-pass membrane protein [UniProt] |
| Highlight | Related news: Studying obesity and appetite control by quantifying orexigenic and anorexigenic hormones; |
| Calculated MW | 37 kDa |
Images (1) Click the Picture to Zoom In
-
ARG56525 anti-Melanocortin 4 Receptor antibody WB image
Western blot: 1) 30 µg of Human cerebella cortex pellet, and 2) 30 µg of Human hippocampus homogenate stained with ARG56525 anti-Melanocortin 4 Receptor antibody.
