ARG45538

anti-Mitochondrial dicarboxylate carrier antibody

anti-Mitochondrial dicarboxylate carrier antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes Mitochondrial dicarboxylate carrier
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Mitochondrial dicarboxylate carrier
Antigen Species Human
Immunogen Recombinant protein containing to human Mitochondrial dicarboxylate carrier.
Conjugation Un-conjugated
Alternate Names SLC25A10; Solute Carrier Family 25 Member 10; DIC; Solute Carrier Family 25 (Mitochondrial Carrier; Dicarboxylate Transporter), Member 10; Mitochondrial Dicarboxylate Carrier; Dicarboxylate Ion Carrier; MTDPS19

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 29 - 31 kDa

Properties

Form Liquid
Purification Affinity purified
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1468 Human SLC25A10

GeneID: 27376 Mouse SLC25A10

Swiss-port # Q9QZD8 Mouse Mitochondrial dicarboxylate carrier

Swiss-port # Q9UBX3 Human Mitochondrial dicarboxylate carrier

Gene Symbol SLC25A10
Gene Full Name Solute Carrier Family 25 Member 10
Background This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Function Catalyzes the electroneutral exchange or flux of physiologically important metabolites such as dicarboxylates (malonate, malate, succinate), inorganic sulfur-containing anions, and phosphate, across mitochondrial inner membrane. [UniProt]
Cellular Localization Mitochondrion inner membrane. [UniProt]
Calculated MW 31 kDa