ARG45435
anti-NHERF2 antibody
anti-NHERF2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NHERF2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NHERF2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human NHERF2. |
| Conjugation | Un-conjugated |
| Alternate Names | SLC9A3R2; Tyrosine kinase activator protein 1; NHE3RF2; E3KARP; Na; +; OCTS2; NHERF-2; Solute carrier family 9 isoform A3 regulatory factor 2; Sodium-hydrogen exchanger regulatory factor 2; NHE3 kinase A regulatory protein E3KARP; NHERF2; SIP-1; SIP1; TKA-1; SRY-interacting protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 45 kDa |
Properties
| Form | Powder |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SLC9A3R2 |
| Gene Full Name | NHERF Family PDZ Scaffold Protein 2 |
| Background | This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
| Function | Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Nucleus. [UniProt] |
| Calculated MW | 37 kDa |
| PTM | Phosphoprotein. [UniProt] |
