ARG45924
anti-NKG7 antibody
anti-NKG7 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NKG7 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NKG7 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to C-terminal region of human NKG7. |
| Conjugation | Un-conjugated |
| Alternate Names | Natural Killer Cell Granule Protein 7; NKG7; GIG1; Protein NKG7; G-CSF-induced gene 1 protein; GIG-1 protein; Granule membrane protein of 17 kDa; GMP-17; Natural killer cell protein 7; p15-TIA-1 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 18 - 25 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NKG7 |
| Gene Full Name | Natural Killer Cell Granule Protein 7 |
| Background | Involved in defense response to protozoan. Located in cytolytic granule membrane and plasma membrane. [provided by Alliance of Genome Resources, Feb 2025] |
| Function | Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases (By similarity). Essential for cytotoxic degranulation of natural killer (NK) cells and CD8+ T-cells and for the activation of CD4+ T-cells following infection (By similarity). Plays a critical role in CD8+ T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules (By similarity). Contributes to NK cell-mediated control of cancer metastasis (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Lysosome. [UniProt] |
| Calculated MW | 18 kDa |
