Overview

Product Description	Rabbit Polyclonal antibody recognizes NQO2
Tested Reactivity	Ms, Rat
Tested Application	FACS, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	NQO2
Antigen Species	Human
Immunogen	Synthetic peptide derived from Human NQO2.
Conjugation	Un-conjugated
Alternate Names	NRH dehydrogenase [quinone] 2; NMOR2; DHQV; Quinone reductase 2; NRH:quinone oxidoreductase 2; QR2; Ribosyldihydronicotinamide dehydrogenase [quinone]; DIA6; EC 1.10.5.1

Application Instructions

Application Suggestion	Tested Application Dilution FACS 1:50 WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	Mouse heart

Properties

Form	Liquid
Purification	Affinity purified.
Buffer	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 18105 Mouse NQO2 GeneID: 291084 Rat NQO2 Swiss-port # Q6AY80 Rat Ribosyldihydronicotinamide dehydrogenase [quinone] Swiss-port # Q9JI75 Mouse Ribosyldihydronicotinamide dehydrogenase [quinone]
Gene Symbol	NQO2
Gene Full Name	NAD(P)H dehydrogenase, quinone 2
Background	This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Function	The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. [UniProt]
Cellular Localization	Cytoplasm. [UniProt]
Calculated MW	26 kDa

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