ARG62572
anti-Nucleolar Antigen antibody [B462]
anti-Nucleolar Antigen antibody [B462] for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections and Human,Rat
Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody
Overview
| Product Description | Mouse Monoclonal antibody [B462] recognizes Nucleolar Antigen |
|---|---|
| Tested Reactivity | Hu, Rat |
| Tested Application | ICC/IF, IHC-Fr, IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | B462 |
| Isotype | IgG1 |
| Target Name | Nucleolar Antigen |
| Antigen Species | Human |
| Immunogen | Myeloid leukemia cell nuclei |
| Conjugation | Un-conjugated |
| Alternate Names | NOL1; p120; NSUN1; NOP120; Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; EC 2.1.1.-; Nucleolar protein 1; Nucleolar protein 2 homolog; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120 |
Application Instructions
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A affinity purified |
| Buffer | PBS (pH 7.2), 0.1% BSA and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 0.1% BSA |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P46087 Human Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase |
|---|---|
| Gene Symbol | NOP2 |
| Gene Full Name | NOP2 nucleolar protein |
| Function | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody |
| Calculated MW | 89 kDa |
| PTM | Citrullinated by PADI4. |
