ARG45314
anti-OGDHL antibody
anti-OGDHL antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Polyclonal antibody recognizes OGDHL |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | OGDHL |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human OGDHL. |
| Conjugation | Un-conjugated |
| Alternate Names | OGDHL; Oxoglutarate Dehydrogenase L; 2-Oxoglutarate Dehydrogenase Complex Component E1-Like; 2-Oxoglutarate Dehydrogenase-Like, Mitochondrial; Alpha-Ketoglutarate Dehydrogenase-Like; Oxoglutarate Dehydrogenase Like; OGDC-E1-Like; EC 1.2.4.2 47; FLJ10851; KIAA1290; YOBELN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 100 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9ULD0 Human 2-oxoglutarate dehydrogenase-like, mitochondrial |
|---|---|
| Gene Symbol | OGDHL |
| Gene Full Name | Oxoglutarate Dehydrogenase L |
| Background | The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The encoded protein down-regulates the AKT signaling cascade and can suppress the growth of cervical cancer cells. [provided by RefSeq, Dec 2016] |
| Function | 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2 while reducing NAD+ to NADH. [UniProt] |
| Cellular Localization | Mitochondrion. [UniProt] |
| Calculated MW | 114 kDa |
