ARG64804
anti-ORAI1 / CRACM1 antibody
anti-ORAI1 / CRACM1 antibody for Western blot and Human
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes ORAI1 / CRACM1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ORAI1 / CRACM1 |
| Antigen Species | Human |
| Immunogen | C-KKQPGQPRPTSKP |
| Conjugation | Un-conjugated |
| Alternate Names | Protein orai-1; CRACM1; Transmembrane protein 142A; IMD9; ORAT1; Calcium release-activated calcium channel protein 1; TAM2; TMEM142A |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96D31 Human Calcium release-activated calcium channel protein 1 |
|---|---|
| Background | The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011] |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 33 kDa |
| PTM | N-glycosylated. Ubiquitinated. Cys-195 is oxidated, leading to inactivate channel activity. |
Images (2) Click the Picture to Zoom In
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ARG64804 anti-ORAI1 / CRACM1 antibody WB image
Western Blot: Human Placenta lysate (35 µg protein in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.03 µg/ml dilution.
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ARG64804 anti-ORAI1 / CRACM1 antibody WB image
Western blot: 35 µg of Human skin lysate (in RIPA buffer) stained with ARG64804 anti-ORAI1 / CRACM1 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.
