Overview

Product Description	Rabbit Polyclonal antibody recognizes Otx1
Tested Reactivity	Hu, Ms, Rat
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	Otx1
Antigen Species	Human
Immunogen	Synthetic peptide of Human Otx1.
Conjugation	Un-conjugated
Alternate Names	Orthodenticle homolog 1; Homeobox protein OTX1

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:1000 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	Mouse brain
Observed Size	37 kDa

Properties

Form	Liquid
Purification	Affinity purified.
Buffer	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 18423 Mouse OTX1 GeneID: 5013 Human OTX1 Swiss-port # P32242 Human Homeobox protein OTX1 Swiss-port # P80205 Mouse Homeobox protein OTX1
Gene Symbol	OTX1
Gene Full Name	orthodenticle homeobox 1
Background	This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Function	Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'. [UniProt]
Cellular Localization	Nucleus. [UniProt]
Calculated MW	37 kDa

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