ARG44545
anti-PAM16 antibody
anti-PAM16 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PAM16 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PAM16 |
| Antigen Species | Human |
| Immunogen | Human PAM16 fusion protein |
| Conjugation | Un-conjugated |
| Alternate Names | PAM16; Presequence Translocase Associated Motor 16; TIMM16; Magmas; Tim16; Mitochondria Associated Protein Involved In Granulocyte Macrophage Colony Stimulating Factor Signal Transduction; Mitochondria-Associated Granulocyte Macrophage CSF-Signaling Molecule; Mitochondrial Import Inner Membrane Translocase Subunit TIM16; Presequence Translocase Associated Motor 16 Homolog; Presequence Translocase-Associated Motor 16 Homolog (S. Cerevisiae); Presequence Translocated-Associated Motor Subunit PAM16; Magmas-Like Protein; CGI-136; SMDMDM; MAGMAS; TIM16 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 14 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity Purified |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9CQV1 Mouse Mitochondrial import inner membrane translocase subunit TIM16 Swiss-port # Q9Y3D7 Human Mitochondrial import inner membrane translocase subunit TIM16 |
|---|---|
| Gene Symbol | PAM16 |
| Gene Full Name | Presequence Translocase Associated Motor 16 |
| Background | This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. |
| Function | Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity. |
| Cellular Localization | Membrane, Mitochondrion, Mitochondrion inner membrane |
| Calculated MW | 14 kDa |
| PTM | Phosphoprotein |
Images (2) Click the Picture to Zoom In
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ARG44545 anti-PAM16 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44545 anti-PAM16 antibody.
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ARG44545 anti-PAM16 antibody WB image
Western blot: HL-60, Hela, Jurkat and LNCAP stained with ARG44545 anti-PAM16 antibody.
