ARG44382
anti-PCF11 antibody
anti-PCF11 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PCF11 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PCF11 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1256-1555 of human PCF11 |
| Conjugation | Un-conjugated |
| Alternate Names | PCF11; PCF11 Cleavage And Polyadenylation Factor Subunit; KIAA0824; Pre-MRNA Cleavage Complex II Protein Pcf11; Pre-MRNA Cleavage Complex 2 Protein Pcf11; PCF11, Cleavage And Polyadenylation Factor II Subunit, Homolog (S. Cerevisiae); PCF11, Cleavage And Polyadenylation Factor Subunit, Homolog (S. Cerevisiae); PCF11, Cleavage And Polyadenylation Factor Subunit, Homolog; PCF11p Homolog |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.01% Thimerosal and 50% Glycerol. |
| Preservative | 0.01% Thimerosal |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O94913 Human Pre-mRNA cleavage complex 2 protein Pcf11 |
|---|---|
| Gene Symbol | PCF11 |
| Gene Full Name | PCF11 Cleavage And Polyadenylation Factor Subunit |
| Background | The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage. |
| Function | Component of pre-mRNA cleavage complex II, which promotes transcription termination by RNA polymerase II. |
| Cellular Localization | Nucleus |
| Calculated MW | 173 kDa |
| PTM | Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation |
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